Extraordinarily Easy to use, Modular HPLC
Each Merit system incorporates the proven, reliable, consistent, high specification, ultra-low drift and durable performance of the trusted Cecil pumps and UV/Visible detectors.
Each system is fully PC controlled, using Merit software, to achieve and save high quality chromatograms. Automatic integration is provided, without the need for further baseline adjustment. Qualitative work is remarkably easy. The fast checking of multi-component samples is easy.
System choices include a CE 4403 UV/Visible detector, a DAD WaveQuest detector, an isocratic CE 4401 pump, a CE 4402 binary pump and a column heater/chiller. Biocompatible options are available.
Set-up of the system hardware is fast, the pump and detector modules each plug into the USB ports of a PC or laptop. The Merit software only takes a few seconds to load and just a few minutes to master. Save HPLC methods and store chromatograms within Merit software or elsewhere on the PC , network or portable drive etc.
In the case of the Merit PC software, chromatograms may be copied and pasted into other software programmes, such as Word or PowerPoint.
All the numerical data points captured within each chromatogram is saved. In two key strokes, data may be manually copied and pasted into Excel or other software spreadsheets.
GLP data such as time, date, serial number of the detector etc. are automatically displayed. Again, data may be copied and pasted into Word, PowerPoint or other software packages.
In addition, the Merit software contains a spacious library. Once a chromatogram is created, it may be saved into the library. In two clicks of the mouse, subsequent chromatograms, may then be compared with the saved chromatograms.
When any two chromatograms are automatically compared with each other, a numerical match index is automatically created. Within a few seconds, a league table of comparable chromatograms is created. This is such a useful facility when performing initial method development and routine elutions.
The minimum PC requirements for Merit PC software are:-
- Personal Computer with Pentium class processor
- Pentium 200 MHz or better
- Microsoft Windows 95, 98, Me, 2000, NT, XP, 7, 8 or later
- Free hard-drive space required: 2 MB
- CD-ROM drive
- XGA or higher resolution monitor
- Monitor resolution 1024 x 768 or better
- Microsoft Mouse or compatible pointing device
- Two available USB ports
These Merit HPLC systems will make life so much easier for so many chemical, biological and materials analysts in so many fields. Multi compound screening scientists, scientists performing initial method development, production scientists, process development chemists, lecturers, teachers and novices, in fact everyone one who wants high impact quick and easy HPLC, will find that a Merit is just right for their needs.
The Merit HPLC systems demonstrate the ultimate in HPLC simplicity. Just inject and go.
Merit HPLC Specifications
Isocratic HPLC Pump CE 4401
Flow Rate |
0.001 to 10mL/min in 0.001 steps |
Flow Reproducibility |
Better than 0.1% |
Maximum Pressure |
40MPa = 400 bar |
Over Pressure Cut-out |
Adjustable between 3 and 40MPa |
Low Pressure Cut-out |
Adjustable between 0 and 40MPa |
Material in contact with fluids |
Ceramic inserts - biocompatible |
|
Check valves – ruby and sapphire |
Pulsation |
Better than ±0.5% at 2mL/min |
PC connection |
USB port |
Binary Low Pressure Mixing HPLC Pump CE 4402
Flow Rate |
0.001 to 10mL/min in 0.001/min increments |
Pressure Range |
0-40MPa over flow range |
Flow Accuracy |
<±0.5% |
Flow Precision |
<0.1% RSD |
Pressure Pulsation |
<±0.5% at 2mL/min |
Gradient Forming |
Binary gradient low pressure mixing and isocratic high pressure operation |
Gradient Control |
Using proprietary high-speed proportioning valves |
Gradient Precision |
Typically 0.2% RSD at 1mL/min |
Material in contact with fluids |
Ceramic inserts, ruby and sapphire check valves, PEEK |
PC connection |
USB port |
UV-Visible Detector CE 4405
Optical System |
Double beam with 1200 lines/mm grating monochromator |
Wavelength Range |
190-700nm |
Wavelength Accuracy |
± 1nm |
Wavelength Precision |
± 0.1nm |
Optical Bandwidth |
8nm |
Straylight |
< .02%, 220nm |
Lamp |
Deuterium lamp with elapsed time indicator |
Absorbance Range |
0.001 to 2A full scale in 11 ranges |
Time Constant |
0.1, 0.2, 0.5, 1, 2, 5 and 10 seconds |
Method Storage |
For up to 30 methods, security protected |
Noise |
± 1 x 10-5 A peak to peak, 220nm, 2s time constant |
Drift |
± 1 x 10-4 A/hour at constant temperature |
Linearity |
Better than 1%, 0.001 – 2A |
Automatic Power-up/off |
Pre-programmed top save warm-up time |
Sample Flow Cell |
8µL x 10mm pathlength |
Refractive Index Sensitivity |
< ± 5 x 10-4 A, water to methanol at 350nm |
Flow Rate Sensitivity |
< ± 3.5 x 10-3 A, for flow change 1-2mL/min, 300nm |
PC connection |
USB port |
WaveQuest D.A.D. Ultra Fast Scanning Detector CE 4403
Optical System |
Double beam |
Monochromator |
With 1200 l/mm holographic grating |
Wavelength Range |
190-700nm |
Optical Bandwidth |
4nm – constant |
Digital Resolution |
1nm |
Wavelength Accuracy |
1nm |
Wavelength Reproducibility |
0.1nm |
Absorbance Range |
0 to 3A |
Scan Speeds |
Up to 1000nm/s |
Baseline Flatness |
± 0.002A over most of range |
Straylight |
<0.02% at 220nm and 340nm |
Noise |
< ±0.5 x 10–5 A at 230nm, 2s air test cell |
Drift |
< ±0.5 x 10–4 A at 230nm, using air test cell |
Calibration and Test |
Automatic at switch-on |
Number of Peak Scans |
Up to 100 peaks for any single elution |
Multiple Scans of a Peak |
Up to 8 scans of any peak |
Scan Trigger |
At start, set Absorbance value, point of inflection or at maximum |
Scan Storage |
Up to 100, password protected |
Method Storage |
Up to 30 methods, password protected |
Heated Oven CE 4407
Temperature Range |
Ambient to 85ºC |
Temperature and Set Point |
3 digit bright LED display |
Temperature Readout Resolution |
0.1ºC |
Temperature Stability |
± 0.01ºC |
Number of Columns |
3 up to 25cm long with pre-columns |
Heating Rate |
30 mins to set point of 65ºC (ambient 25ºC) |
Stabilising Time |
Negligible when set point reached |
Leak Detection |
Vapour detector – adjustable shut down level |
Autosampler CE 4408
Carousel capacity |
50 vials, 2mL |
Loop sizes |
10μL - 200μL |
Injection valve |
Rheodyne 7900-000 |
Sample loop flush |
Operator selectable |
Volume reproducibility |
Better than 0.05% |
Carry over (with wash) |
Better than 0.005% |
Replicate injection |
up to 15 |
Cycle time |
12s minimum |
Solvent Degasser CE 4020
Number of flow channels |
2 |
Maximum Flowrate |
10mL/min |
Materials Contacting Solvents |
PEEK, glass filled PTFE, Teflon AF |
Gas removal |
To better than 1ppm at 1mL/min |
Isocratic HPLC Pump CE 4401
Flow Rate |
0.001 to 10mL/min in 0.001 steps |
Flow Reproducibility |
Better than 0.1% |
Maximum Pressure |
40MPa = 400 bar |
Over Pressure Cut-out |
Adjustable between 3 and 40MPa |
Low Pressure Cut-out |
Adjustable between 0 and 40MPa |
Material in contact with fluids |
Ceramic inserts - biocompatible |
|
Check valves – ruby and sapphire |
Pulsation |
Better than ±0.5% at 2mL/min |
PC connection |
USB port |
Isocratic HPLC Pump CE 4401
Flow Rate |
0.001 to 10mL/min in 0.001 steps |
Flow Reproducibility |
Better than 0.1% |
Maximum Pressure |
40MPa = 400 bar |
Over Pressure Cut-out |
Adjustable between 3 and 40MPa |
Low Pressure Cut-out |
Adjustable between 0 and 40MPa |
Material in contact with fluids |
Ceramic inserts - biocompatible |
|
Check valves – ruby and sapphire |
Pulsation |
Better than ±0.5% at 2mL/min |
PC connection |
USB port |
====================================================
非常简单易用,模块化高效液相色谱法
每个优点系统采用了经过验证的,可靠的,一致的,高规格,超低漂移和信任塞西尔的耐用性能泵和紫外/可见光检测器。
每个系统完全电脑控制,采用优异的软件,来实现和保存高质量的色谱图。自动一体化设置,而不需要进一步的基线调整。定性的工作是非常容易的。多组分样品的快速的检查也容易。
系统选择包括CE 4403紫外/可见光检测器,二极管阵列检测器WaveQuest ,等度CE 4401泵, CE 4402二元泵和色谱柱加热器/冷却器。生物相容性可供选择。
建立了系统的硬件速度快,泵和检测每个模块插入到PC或笔记本电脑的USB端口。优异的软件只需要几秒钟加载,只是几分钟的时间来掌握。保存的HPLC方法,并在优异的软件或PC ,网络或可移动驱动器等其他地方商店色谱图
在优异的PC软件的情况下,色谱图可以复制并粘贴到其他软件程序,如Word或PowerPoint 。
所有每个色谱图中捕获的数值数据点被保存。在两个关键笔画,数据可以手动复制并粘贴到Excel或其他电子表格软件。
GLP数据,如时间,日期,检测器的序列号等被自动显示。同样,数据可以被复制并粘贴到Word中, PowerPoint或其他软件包。
此外,优异的软件包含了一个宽敞的图书室。一旦色谱创建时,它可被保存到库中。在两次点击鼠标,则后续的色谱图,然后可以与所保存的色谱图相比较。
当任意两个色谱图会自动相互比较,数值匹配索引被自动创建。几秒钟内,可比较色谱图的名次表被创建。这是多么有用的工具执行初始方法开发和日常洗脱时。
为优异的PC软件的最低PC要求是: - •个人电脑与奔腾级处理器 • Pentium 200 MHz或更好 •微软Windows 95 , 98 , ME,2000 , NT,XP , 7 , 8或更高版本 •所需的可用硬盘空间: 2 MB • CD -ROM驱动器 • XGA或更高分辨率的显示器 •显示器分辨率1024× 768或更高 • Microsoft鼠标或兼容的指针设备 •两个可用的USB端口
这些优异的HPLC系统将让生活变得更轻松了这么多的化学,生物和材料分析在如此众多的领域。多化合物筛选的科学家,执行初始方法开发,生产的科学家,工艺开发的化学家,讲师,教师和新手,其实大家一个谁愿意高抗冲快速简便高效液相色谱科学家,会发现一个优点是正好适合他们的需求。
优异的HPLC系统表现出极致的高效液相色谱法简单。刚刚注入而归。
技术规格:
等度HPLC泵CE 4401 流量0.001〜 10ml/min时0.001步骤 流量重复性优于0.1% 最大压力为40MPa = 400吧 过压开孔可调节3至为40MPa 低压切出可在0和为40MPa 材料与液体陶瓷刀片的接触 - 生物相容性 止回阀 - 红宝石和蓝宝石 脉动小于± 0.5 %提升以2mL/min PC连接USB端口
二元梯度混合HPLC泵CE 4402 流量0.001〜 10ml/min时在0.001/min增量 压力范围0 -为40MPa以上流量范围 流量精度< ± 0.5 % 流量精度< 0.1 %RSD 以2mL/min压力脉动< ± 0.5 % 梯度形成二元梯度低压混合和等度高压操作 梯度控制使用专有的高速比例阀 梯度精度一般为0.2 %,相对标准偏差为1ml/min 材料与液体陶瓷刀片,红宝石和蓝宝石止回阀, PEEK接触 PC连接USB端口
紫外 - 可见光检测器CE 4405 光学系统双光束1200线/ mm的光栅单色仪 波长范围190- 700nm的 波长精度± 1nm的 波长精度±为0.1nm 光学带宽为8nm 杂散光< .02 % ,220纳米 灯氘灯与经过时间指示器 吸光度范围0.001〜 2A满量程的11范围 时间常数0.1,0.2, 0.5,1, 2,5秒和10秒 方法存储多达30的方法,安全保护 噪声± 1 ×10-5峰值到峰值,220纳米, 2秒的时间常数 漂移± 1× 10-4 /小时恒温 线性度优于1% , 0.001 - 2A 自动Power-up/off预编程的顶级节省预热时间 样品流通池8μL ×10毫米光程 折射率灵敏度< ± 5× 10-4 ,水与甲醇在350nm 流量灵敏度< ± 3.5× 10-3 ,用于流量变化1-2mL/min , 300nm的 PC连接USB端口
WaveQuest D.A.D.超快速扫描探测器CE 4403 光学系统双光束 单色仪采用1200条升/毫米全息光栅 波长范围190- 700nm的 光学带宽4nm的 - 恒 数字分辨率为1nm 波长准确度为1nm 波长重复性为0.1nm 吸光度范围:0〜 3A 扫描速度高达1000nm的/秒 基线平直度± 0.002A在大部分范围内 杂散光<在220nm和340nm的0.02 % 噪声< ± 0.5× 10-5处为230nm ,2S空气测试单元 漂移< ± 0.5× 10-4在230nm处,用空气测试单元 校准和测试时自动接通 扫描次数多达100个峰任何单一洗脱 峰值高达8扫描任何峰多次扫描 扫描触发器在启动,设定吸光度值,拐点或最大 扫描存储最多100 ,密码保护 方法存储多达30个方法,密码保护
柱温箱 CE 4407 温度范围室温至85℃ 温度和设定点3位高亮LED显示屏 温度读数分辨率0.1 ºC 温度稳定性± 0.01 ºC 列高达3到25cm长,预列数 升温速率30分钟,以设定点为65 ℃(室温25 ℃) 稳定价格的时间可以忽略不计,当设定点达到 泄漏检测蒸气检测仪 - 可调节的关机水平
自动进样器CE 4408 旋转盘 容量50瓶, 2毫升 环尺寸10μL - 200μL 进样阀的Rheodyne 7900-000 样品环冲洗操作可选 体积重现性优于0.05% 结转(含洗)优于0.005 % 复制注射高达15 周期时间最短12秒
溶剂脱气机CE 4020 流动通道2的数 最大流速10ml/min时 物料接触溶剂聚醚醚酮,玻璃填充聚四氟乙烯,聚四氟乙烯自动对焦 气体脱除要低于1PPM更好地为1mL/min
配置表:
The following are included as standard, within each Merit HPLC system: All system modules Injection valve and loop Interconnection and power cables. Column and valve panel where appropriate. Pipes and tubing. Sample injection syringe . Solvent bottles with drilled lids. Solvent inlet filter. Standard flowcell
以下是作为标准,每优异HPLC系统中: 所有的系统模块 进样阀和循环 互连电缆和电源线。柱和阀板在适当情况下。 管道和管件。 样品注射器。 溶剂瓶与盖钻。溶剂入口过滤器。 标准流通池。
|